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KMID : 0369820090390020093
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Jorunal of Korean Pharmaceutical Sciences
2009 Volume.39 No. 2 p.93 ~ p.95
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Comparative evaluation of water vapor transmission rate of PVA/Dextran blended hydrogel using European Pharmacopiea and Japanese Industrial Standards method
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Hwang Ma-Ro
Oh Dong-Hoon
Kim Jong-Oh
Lee Jeong-Hoon
Woo Jong-Soo
Yong Chul-Soon
Choi Han-Gon
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Abstract
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To compare the water vapor transmission rate (WVTR) of PVA/Dextran blended hydrogel obtained by European Pharmacopiea (EP) and Japanese Industrial Standards 1099 (JIS) method, the hydrogels with various PVA/Dextran rates were prepared and their WVTR values were then checked. As dextran in the hydrogel was increased, the WVTR of hydrogel was increased. The WVTR of hydrogels were 660-1500 and -day in EP and JIS method, respectively. There were no significant differences between the WVTRs of the hydrogels obtained by EP and those obtained by JIS method. Thus, JIS method was recommended as a WVTR method of hydrogel due to relatively simpler and shorter time.
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KEYWORD
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Water vapor transmission, wound dressing, hydrogel, European Pharmacopiea, Japanese Industrial Standards
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